The global next generation sequencing market size is expected to reach USD 23.7 billion by 2027, expanding at a CAGR of 11.7%, according to a new report by Grand View Research, Inc. Numerous advantages offered by high throughput sequencing over other genetic technologies such as sanger-seq and microarray is one of the key driving forces of the market for Next Generation Sequencing (NGS). Furthermore, increasing availability of low input DNA sampling methods that decrease the overall operational costs is anticipated to accelerate the use of next generation sequencing across various research and clinical applications.
Technology
offered by New England Biolabs that employs magnetic beads in the template
assembly process is anticipated to significantly improve the sample preparation
protocols for next generation sequencing. Furthermore, recent technological
advancements such as the use of Laboratory Information Management System (LIMS)
for genome library automation allow next generation sequencing in a single day
at a reasonable cost. These advancements are anticipated to proliferate the
number of users of next generation sequencing over the forecast period.
This
technology has captured the attention of several companies and investors
operating across various domains including basic research, drug discovery and
development, reproductive health, and consumer genomics. In addition, the
plummeting cost and the added value of next generation sequencing data over
conventional ones is anticipated to positively impact the diversification of
this technology in other clinical areas, resulting into a lucrative revenue
growth.
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Further key
findings from the report suggest:
- In 2019, oncology was
estimated as the application with the largest revenue share in the market
for next generation sequencing
- This can be attributed to
the fact that the technology has been largely adopted to decipher the link
between cancer and genetics
- Moreover, NGS-based genetic
testing for cancer predisposition can significantly improve the health
outcome and reduce the mortality rate, thereby driving adoption in this
segment
- The targeted sequencing
segment has dominated the revenue share owing to its various benefits over
the whole genome segment with respect to the depth of coverage and
multiplexing capacities
- Significant price drop in
sequencing the whole genome is anticipated to drive the segment at a
lucrative growth rate
- Based on workflow,
sequencing accounted for the major revenue share in 2019 in the market for
next generation sequencing and is anticipated to maintain its dominance
over the forecast period
- Being a key step, the
end-users are making major investments in the seq-step, compared to sample
preparation and data analysis
- Moreover, the key developers
are engaged in introducing new seq-platforms with enhanced capabilities
and efficiency. These factors have led the segment in terms of revenue
over the past years
- Academic research entities
are the largest end-users in terms of revenue generation owing to the high
penetration of seq-technology in research activities
- On the other hand, this
technology is making continued growth in clinical research and within
clinical settings
- A substantial number of
researchers are engaged in conducting translational research to accelerate
the adoption of seq-technology in clinical diagnostics
- North America accounted for
the maximum revenue share owing to the presence of integrated
platform base in U.S.
- Presence of Illumina, the
major player of next generation sequencing market for U.S. is another
major factor that has driven the revenue share of this region in the past
years
- Asia Pacific is projected to
mark fastest growth owing to the increase in number of domestic developers
in China coupled with the expansion of molecular diagnostics area
- Some major participants in
the market for next generation sequencing are Illumina Inc.; F Hoffman-La
Roche Ltd.; QIAGEN; Thermo Fisher Scientific Inc.; and BGI
- The companies are
collaborating with diagnostic players to extend the use of their platforms
in clinical settings
- For instance, Illumina has
partnered with China’s KingMed Diagnostics for use of its platform in
oncology and hereditary disease testing.
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Grand View Research has segmented
the global next generation sequencing market based on application, technology,
workflow, end use, and region:
NGS Application
Outlook (Revenue, USD Million, 2016 - 2027)
- Oncology
- Diagnostics and Screening
- Screening
- Sporadic Cancer
- Inherited Cancer
- Companion Diagnostics
- Other Diagnostics
- Research Studies
- Clinical Investigation
- Infectious Diseases
- Idiopathic Diseases
- Inherited Diseases
- Non-Communicable/Other
Diseases
- Reproductive Health
- NIPT
- Aneuploidy
- Microdeletions
- PGT
- Newborn Genetic Screening
- Single Gene Analysis
- HLA Typing/Immune System
Monitoring
- Metagenomics, Epidemiology
& Drug Development
- Agrigenomics & Forensics
- Consumer Genomics
NGS Technology
Outlook (Revenue, USD Million, 2016 - 2027)
- Whole Genome Sequencing
- Whole Exome Sequencing
- Targeted Sequencing &
Resequencing
- DNA-based
- RNA-based
NGS Workflow
Outlook (Revenue, USD Million, 2016 - 2027)
- Pre-sequencing
- NGS Library Preparation
Kits
- Semi-automated Library
Preparation
- Automated Library
Preparation
- Clonal Amplification
- Sequencing
- NGS Data Analysis
- NGS Primary Data Analysis
- NGS Secondary Data Analysis
- NGS Tertiary Data Analysis
NGS End-use Outlook
(Revenue, USD Million, 2016 - 2027)
- Academic Research
- Clinical Research
- Hospitals & Clinics
- Pharma & Biotech
Entities
- Other Users
NGS Regional
Outlook (Revenue, USD Million, 2016 - 2027)
- North America
- U.S.
- Canada
- Europe
- Germany
- U.K.
- Asia Pacific
- China
- Japan
- Latin America
- Brazil
- Middle East Africa
- South Africa
About Grand View Research
Grand View Research, Inc. is a U.S. based
market research and consulting company, registered in the State of California
and headquartered in San Francisco. The company provides syndicated research
reports, customized research reports, and consulting services. To help clients
make informed business decisions, we offer market intelligence studies ensuring
relevant and fact-based research across a range of industries, from technology
to chemicals, materials and healthcare.
For more info visit @ https://www.grandviewresearch.com
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