The global T-cell therapy market size is expected to reach USD 7.51 billion, expanding at a CAGR of 15.4% by 2026, according to a new report by Grand View Research, Inc. The landmark approvals of Yescarta and Kymriah have spurred unprecedented advancements in the market. The launch of these breakthrough therapies has bolstered cash inflow for innovation, thereby driving the growth.
Expansion
of the market for T-cell therapy significantly relies on shifting preference
from first-line stem cell transplants and chemotherapy to third-line CAR T-cell
therapy. Moreover, the ever-expanding plethora of medical conditions for which
the T cell therapies is projected to bode well for the market growth. Rise in
oncological disorders is projected to drive interest as well as investments in
the T-cell therapy market in near future.
In
contrast with the small-molecule landscape, engineered T cells market landscape
is distinguished by an extensive network that encompasses several entities
marked by connections academically, financially, and via technology licensing.
Research bodies, and manufacturers, and regulators engage in assessing the
long-term efficacy and safety of therapies to ensure safe access to patients.
By
far, the antigen challenge and linked toxicity concerns have impeded the
development of CAR T therapies in non-hematological malignancies. Market
players are applying a data-driven approach of exploring this space to mitigate
the challenge and expand the usage of T-cell therapy in indication type such as
brain cancer and melanoma.
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Further key
findings from the report suggest:
- In the coming years, the
number of hospitals implementing CAR T therapies is expected to increase,
thereby driving the commercialized business model
- Research-based business
modality accounted for the highest revenue generation over the past years,
attributed to the presence of several research programs
- CAR-T cell therapy market
share accounted for the larger revenue share of the overall T-cell therapy
market in 2018 owing to the highest investment by sponsors in this therapy
type
- Presence of approved
products for B cell lymphoma and acute lymphocytic leukemia has resulted
in the dominance of hematological malignancies in the market
- Therapy for solid tumors is
expected to emerge as the lucrative source of revenue generation in the
forthcoming years
- Rising research activities
in CAR T-cell therapy for solid tumors, particularly, for brain &
central nervous system and melanoma, is expected to benefit the key
players
- North America led the global
market in 2018 owing to the presence of a large number of cancer centers
engaging in research activities. Moreover, U.S.-based pharma companies
like Pfizer Inc. and Celgene Corporation have shifted their focus from
conventional drug development to T-cell therapy space
- Asia Pacific is estimated to
witness the fastest growth with China at the forefront. China has
surpassed the number of CAR T clinical trials conducted in U.S. Moreover,
Novartis is strategizing to secure approval for Kymriah by China
regulatory authorities in the forthcoming years
- Gilead Sciences, Novartis
AG, TCR2 Therapeutics Inc., Celgene Corporation, Sorrento Therapeutics,
bluebird bio, and Fate Therapeutics are some key players operating in the
market. They engage in mergers and acquisitions with therapy developers.
Acquisition of Juno Therapeutics by Celgene in January 2018 and Kite
Pharma by Gilead in August 2017 are some notable examples of acquisitions
in this market
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Grand View Research has segmented
the T-cell therapy market on the basis of modality, therapy type, indication,
and region:
T-cell Therapy
Modality Outlook (Revenue, USD Million, 2015 - 2026)
- Research
- Commercialized
T-cell Therapy Type
Outlook (Revenue, USD Million, 2015 - 2026)
- CAR T-cell Therapy
- T Cell Receptor (TCR)-based
- Tumor Infiltrating
Lymphocytes (TIL)-based
T-cell Therapy
Indication Outlook (Revenue, USD Million, 2015 - 2026)
- Hematologic Malignancies
- Lymphoma
- Leukemia
- Myeloma
- Solid Tumors
- Melanoma
- Brain & Central Nervous
System
- Liver Cancer
- Others
T-cell Therapy
Regional Outlook (Revenue, USD Million, 2015 - 2026)
- North America
- U.S.
- Canada
- Europe
- Germany
- UK
- Asia Pacific
- Japan
- China
- Latin America
- Brazil
- Middle East and Africa (MEA)
- South Africa
About Grand View Research
Grand View Research, Inc. is a U.S. based
market research and consulting company, registered in the State of California
and headquartered in San Francisco. The company provides syndicated research
reports, customized research reports, and consulting services. To help clients
make informed business decisions, we offer market intelligence studies ensuring
relevant and fact-based research across a range of industries, from technology
to chemicals, materials and healthcare.
For more info visit @ https://www.grandviewresearch.com
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